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Even though the precise mechanism by which acid causes heartburn and pain is not known, the current understanding is as follows: acid and pepsin induce injury to the squamous epithelium and as a result the epithelium becomes porous and leaky.
However, the current understanding is limited to the qualitative or empirical level due to the complex nonlinear mechanics involved in soft material fracture.
In conclusion, the current understanding is that symptomatic PCC is best managed jointly by the endoscopist and surgeon with sequential interventions designed initially to establish and maintain biliary drainage, then to decompress the portal cavernoma and, finally, if required, second stage biliary surgery or endotherapy for biliary strictures.
The mechanisms of ramucirumab-related GI perforation remain unclear, and the current understanding is based primarily on other anti-angiogenesis inhibitors.
This could lead to some courageous marketing choices in September when the new iPhone handsets are announced, because the current understanding is that 5G hardware will not be available for Apple's upcoming smartphones, and may not make an iOS-powered appearance until 2020.
The current understanding is that the sword itself was made for the Tynwald meetings of 1417 or 1422.
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Missing from the current understanding are the inner workings of the enzymatic reaction mechanism that achieve such a balance, and, in particular the role the enzyme environment plays in asserting strict control over Ado· during catalysis.
The daily task of science is to identify the ways in which our current understanding is lacking.
"I'd like to see a company which tries to strengthen relationships between dogs and people by getting people excited about the fact that science has just begun to investigate the dog mind, and our current understanding is minimal.
Current understanding is that the carbon reagents decompose in the presence of a catalyst to give C atoms that then combine or extrude into carbon nanotubes, fibers (or spheres).
Our current understanding is that the NFAT family of transcription factors arose around the time that vertebrates emerged, around 500 million years ago (Wu et al, 2007).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com