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In the absence of these genes, the organism has to be supplemented for the corresponding essential nutrient; otherwise growth cannot be achieved.
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Hu et al.[ 8] and Roemer et al. [ 9] have respectively identified drug targets for Aspergillus fumigatus and Candida albicans based on corresponding essential genes identified from mouse models.
To further confirm the specific involvement of only pilus 2a in biofilm formation we investigated the ability to adhere to polystyrene plates of biofilm-forming strains expressing the other two pilus types (pilus 1 or pilus 2b), in which we knocked out the corresponding backbone protein essential for pilus polymerization (Figure 5A).
Individual COG phylogenetic profiles may only show a relatively weak correlation with a phenotype profile, even when the corresponding gene is essential for the phenotype.
As each circle lies above and to the left of the corresponding square, the essential sample distribution is evidently shifted lower with respect to GC-divergence, but higher with respect to DRA-divergence.
All snoRNA-directed rRNA modifications are individually non-essential, and the corresponding snoRNAs are similarly non-essential for the processing of pre-rRNA, ribosome synthesis and viability (Kiss, 2002).
As commented above, the data consists of knock-out and hypomorph experiments, with the latter corresponding to essential genes [ 16].
The power and flexibility of the corresponding computational tools become essential success factors for the whole research process.
Quantitative data were obtained by comparing the analyte/anisole area ratios in the standard solutions with the corresponding ratios in the essential oil samples solutions.
In the case of hydrogen peroxide synthesis, it is important that the non-selective formation of water is minimised, and in the case of alcohol oxidation to the corresponding aldehyde it is essential that the over-oxidation to the carboxylic acid is minimised.
The corresponding extensions might be essential for regulation of the apicoplast proteins and their translocation into the apicoplast.
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