Exact(15)
"We take seriously the idea that in a developing embryo cells need to "know" their position in order to make the correct developmental decisions," said Petkova, Class of 2012.
Therefore, a gene must not only be composed of the DNA sequence that is actually transcribed, but it must also include an adjacent regulatory, or control, region that is necessary for the transcript to be made in the correct developmental context.
It occurs at the correct developmental time in late third instar eye development (data not shown).
Briefly, at the correct developmental time point, the synchronized worms were washed in M9 and sucrose floated.
Thus, ESE3 could be a critical factor to maintain the equilibrium between competing stimuli and allow the correct developmental and differentiation programs to proceed.
A minimum of 5 embryos of the correct developmental stage was considered in each case.
Similar(45)
Such regions have been shown to contain all the necessary sequences for correct developmental regulation of expression of a number of developmentally regulated genes in Dictyostelium and there have been no reports of other regions being required.
The two different nuclear phenotypes underlie specific transcriptional and translational programmes central to the acquisition of a correct developmental competence or developmental failure [ 2932]2932]
Correct developmental stages were verified based on morphological features.
It has been reported that DNA methylation can prevent gene activation and restrict expression for correct developmental stage [ 66].
We conclude that Frabin/Fgd4 function is not only required for correct developmental myelination but also specifically and prominently for myelin maintenance.
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