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The proteasome inhibitor bortezomib is now the cornerstone of combination therapy of multiple myeloma (MM).
Antiretroviral regimens based on human immunodeficiency virus-1 protease inhibitors are the cornerstone of combination antiretroviral therapy because of their antiviral efficacy and high genetic barrier.
26 RAAS blockade is usually the cornerstone of combination therapy, with a thiazide diuretic or a calcium-channel blocker often recommended as an add-on.
ARVs represent the cornerstone of combination HIV prevention; optimizing the clinical and public health benefit(s) of these agents is of the greatest priority.
Trastuzumab, which targets the extracellular domain of HER2, has become the cornerstone of combination therapies for HER2-positive early and advanced breast cancer based on the results of numerous clinical trials [ 6, 8, 9].
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16 We have also observed over the years that two of the oldest drugs, cisplatin and 5-FU, are still worthwhile, and are considered as the cornerstone of many combination therapies.
Artemisinin derivatives are potent antimalarials that are the cornerstone of currently recommended drug combination to treat P. falciparum malaria [ 9].
Though Cisplatin combination chemotherapy is the cornerstone of treatment of many cancers, serious adverse effects offset the productivity of treatment and renders the chemotherapy unsustainable.
5-Fluorouracil, which is also used in the treatment of breast, stomach, and pancreatic cancer, remains the cornerstone of CRC treatment, although widely used in combination with several other drugs (Kopetz, 2008).
Small-cell lung cancer is highly sensitive to chemotherapy and combination regimens have been the cornerstone of treatment since the 1970s.
2 3 Although inhaled corticosteroids anti-inflammatory corticosteroids anti-inflammatorye controllere of preventing asthma exacerbations, 4 5 6 several other agents or combination strategies have been investigatedrugs
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