Sentence examples for the core trial from inspiring English sources

The CORE trial will take almost 4 years to complete.

In the core trial, the starting dose for both insulins was 10 Units.

Baseline was defined as the time of randomization in the core trial.

One death due to pulmonary embolism was reported in the raloxifene group during the 4 years of the CORE trial.

The interviewer told participants that she worked alongside the trial but was not part of the core trial team.

The rest of this report will detail the protocol for the quantitative analysis of the core trial (Themes 1-3).

A summary of the related qualitative work (Themes 4 and 5) can be found in Figure 4 and 5. Themes 1-3 were all based on the same core trial design and involved the same population criteria and interventions, but the samples and outcome assessments differed.

To assess the immunogenicity of degludec and to minimize interference with antibody measurements, a 1-week basal insulin washout period was scheduled at end of treatment of both the 52-week core trial and the extension period, during which participants in both arms were switched to twice-daily neutral protamine Hagedorn (NPH) insulin (with a 20% reduction in total basal dose).

In the extension trial set, laboratory-measured fasting plasma glucose decreased rapidly in the first 12 weeks and did not increase over the remainder of the 52-week core trial (Fig. 1d).

The principal findings of the 52-week, core trial 2, namely that degludec provides improved glycaemic control similar to glargine (similar HbA1c reduction with greater reduction in fasting plasma glucose), using similar insulin doses, with lower rates of nocturnal and severe hypoglycaemia and similar weight gain, were sustained for a full 104 weeks of treatment.

Subjects who completed the 52-week core trial and provided informed consent entered the 52-week extension trial maintaining prior randomization.