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Bossis and several of his colleagues described the considerable difficulty they had recruiting patients from N.Y.U.
He pointed out the considerable difficulty evaluating the effect of the drug in PSH, given the marked and spontaneous variation in attack frequency.
The version of the report released to the public does not identify the service involved, but goes on to highlight the "considerable difficulty" MI5 has accessing content from six US-headquartered companies: Facebook.
These two views are not necessarily mutually exclusive, but they do point out the considerable difficulty in determining the influence of substrate (litter, SOM), microbial community composition (Muller et al. 1999) and abiotic factors such as temperature and water flux on DOC production and flux (Brooks et al. 1999).
It said that British citizens are "unnecessarily exposed to greater risk" because of the "considerable" difficulty UK intelligence agencies have in accessing online communications from US providers such as Apple, Facebook, Google, Twitter, BlackBerry, Yahoo and Microsoft.
This all highlights the considerable difficulty of effectively bringing about a healthy change in attitudes towards being overweight in settings where poverty and HIV are pervasive.
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These diagrams glossed over the considerable difficulties of mixing materials from two different species.
It's not quite Mr. Romney's constant description of a tattered and threadbare country, but it does acknowledge the considerable difficulties that remain.
Veronika Part and Michele Wiles, in the principal roles, managed the considerable difficulties of their solo sections, which set big jumps at a plush, adagio pace, but they looked less at ease in their counterpointed play against each other.
However, it does recognise the considerable difficulties you have faced over the last few months and says: "Although we don't accept liability for the damage, as a gesture of goodwill we are proposing that we will provide the work to establish a new licence and the supervisory work free of charge for a new pipe to be installed alongside a nearby bridge".
An interpretational methodology designed to overcome the considerable difficulties in obtaining reproducible, meaningful parameters of structural disorganisation is also presented, and should prove useful for future Raman applications.
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