Table 1 lists each human serpin, together with brief notes in regards to each molecules function and the consequence (where known) of dysfunction or deficiency.
Probing those consequences where the geometry is highly twisted and malleable, said Dr. Frederick K. Lamb, a physicist at the University of Illinois at Urbana-Champaign, "is one of the major problems of modern physics and astrophysics, and it's a regime in which we have had very little or no information".
She argued that the majority were effectively suggesting "the general public can pick up the tab" instead, and warned of dire consequences: "Where is the stopping point to the 'let the government pay' alternative?
In this way, much of the reasoning was based on assumptions and deliberations about consequences, where the physician would aim to make the decision he or she believed benefitted the patient the most short term as well as long term.
Of course you need to be proportionate, of course you need to be careful, of course you don't want to create unintended consequences where the taxpayer ends up footing more of the bill or we create more social problems or problems of law and order".
For this reason, the optimal application of the personalisation algorithms to a real service, implies studies of long-term consequences, where the system will be used by a big number of users for 6 12 months.
Mass consumer confusion created by government bureaucrats won't protect privacy; it will make consumers simply give up -- another damning case of the law of unintended consequences where rules intended to give more protection gum up the works so badly that they end up offering less.
And in a grim example of the law of unintended consequences, where urban communities do succeed in changing their neighbourhood for the better, the result is often higher rents, more interest from developers, and the gradual displacement of the very people who forced those changes into being.
They exist in a place with no consequences, where the only person you have to please is yourself.
Now (1) is a variant of Sidgwick's thesis that common-sense moralities tend to solidify around rules which are believed to have generally beneficial consequences, where the benefit is cashed out in terms of human welfare.
