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The consequences of this modification for the extraction of a polymer from a porous matrix are explored in detail, and the formal results are explicitly illustrated by means of a specific solution.
In the present work, our goal was to design a new type of nanocapsules, using chitosan chemically modified with poly ethylene glycol) (PEG) (0.5% and 1% pegylation degree) and to investigate the consequences of this modification on the in vitro and in vivo behaviour of the nanocapsules.
The consequences of this modification include: 1) Conjugation of VHL to SUMO1 which alters protein-protein interaction with its substrates; and 2) Competition with other posttranslational modifiers.
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Moreover it will be important to define to what extent the consequence of this modification overlaps with the inhibitory effect of Ser-9 phosphorylation as well as other regulatory mechanisms that target GSK3β [ 43- 45].
The consequences of this thermodynamic modification are studied in detail.
We monitored the consequences of these modifications on Ca2+ binding by isothermal titration calorimetry, thermal stability and conformational and crystal structure analyses.
HPLC, mass spectrometry and antimicrobial assays were carried out to explore the consequences of the modifications on the serum stability and microbicidal activity of the peptides.
Nonetheless, our results provide direct evidence that transmission of the sex chromosomes through the male or female germline results in differential epigenetic modification and demonstrates the consequences of these modifications for genome-wide gene expression.
While evaluating overall levels of an oxidative modification is useful as an indication of oxidative stress in a tissue, knowing which specific proteins are targeted by posttranslational modifications can further provide an understanding of the consequences of the modifications.
The consequence of this pressure modification is interpreted as a local variation/increase in the effective buoyancy acting on the swarm bubbles being overtaken by the cap; the bubble rise velocity increases as the vertical distance between the bubble and the cap decreases and, under sufficient pressure gradient, it reaches the cap rise velocity.
Whereas a plethora of information has been obtained regarding the machinery that modifies H3K4 methylation [3], little is known about the physiological consequences of this modification.
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