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What are the consequences of the expression of mHtt in other brain cell populations and to what extent it contributes to brain degeneration?
We investigated the consequences of the expression of SP-C with the mutation A116D for cell homeostasis and signaling in stably transfected MLE-12 cells.
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The Congress, while it has a right to express its opinions on critical issues of the day, also must be cognizant of the consequences of the expressions of those opinions".
Another point of our research was the consequence of the expression of proteins and genes with opposite effects on apoptosis.
To be logical and direct demonstration of the consequences of the low expression levels of miR-22 in GC, we performed miR-22 inhibition experiments by anti-miR-22 thensfection in the AGS cell line, in which miR-22 expression was higher than other three GC cell lines.
We further examined the consequences of the down-regulated expression of xbp1 by expressing xbp1-RNAi constructs or using the xbp1 mutant chromosome xbp1 K13803 in the HTorAΔE flies.
It should be noted that we have deliberately chosen a unilateral delivery of the NDI1 gene to achieve unequivocal assessment of the consequences of the target gene expression by comparing the two sides in the same animal.
The consequences of the modulation of miRNAs on the expression levels are measured by using different tools, including RT-PCR or microarrays.
Whether the low proliferation rate of HP1γ knocked-down ESC is the cause or the consequence of the sporadic expression of differentiation genes is not elucidated here.
Therefore, we postulated that the elevated production of sBAFF was the consequence of the enhanced expression of the BAFF gene.
Next, we evaluated the consequence of the neuronal expression of Trap1 on phenotypes associated with muscle degeneration.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com