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A lack of functional assays has hampered the conclusive validation of the consequences of these variants.
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It must be noted that our parameter CCL is measured by Raman spectroscopy and represents collagen quality, while no conclusive validation has been performed yet on the measurement of mature-immature cross-link with this technology.
This is mainly because conclusive validation based on a large sample is still missing.
Conclusive validation of novel antifungal targets from both a chemical and genetic perspective provides a critical first step in reversing this trend.
This does not therefore provide conclusive validation of a particular gene model over another; rather it offers additional support at the protein level that a particular isoform is expressed from that particular genomic locus.
These bands are emerging from amide vibrations of the backbone; they reflect secondary structure of the protein and are expected to be affected by cross-links [ 37], even though no conclusive validation has been performed for Raman spectroscopy yet, as for FTIR [ 29].
The statistical significance was modest and will require further study for conclusive validation.
It was not the conclusive factor.
The conclusive answer must be no.
The conclusive remarks can be drawn as follows.
X-ray crystal analysis, whenever feasible, offered the conclusive evidence.
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