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Exact(33)
It denotes the concentration which causes an effect of xx %.
Generally, it is the concentration which is required to kill half of the original cells.
In other words, MIC is the concentration which impedes and absolutely prevents bacterial growth.
Limit of detection (LOD) is defined as the concentration which has a signal-to-noise ratio of 3 1.
The concentration, which corresponds to tm = 1, was found by extrapolation of tm − C curves (inset of Figure 8).
ECxx has a clear interpretation as it is always an estimate of the concentration which causes a response of xx %.
Similar(27)
The concentrations which inhibited 50% of cell growth (IG50) and killed half of the cells (IC50) were calculated.
When cells were able to survive at any given concentration of the drug, they were passaged in the concentrations which were 1.5-fold higher.
It therefore tends to overestimate the concentrations, which is evidenced by its higher bias and RMSPE.
Notably, induction of NQO1 is evident at lower inducer concentrations compared with the concentrations, which cause HSP70 upregulation.
ErPC3 was applied at the concentrations which are known to result in pronounced apoptosis (U87MG: 45 μM; U118MG: 15 μM) [ 7, 8].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com