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The improvement tends to raise as the complexity of the analyzed instance increases.
This may be explained by the fact that the number of modes depends partially on the complexity of the analyzed signal, on its information content.
It is important also to note that, due to the complexity of the analyzed data, a SVM classifier with a RBF kernel which is known to be a strong classifier should be used as the component classifier of the network.
Issues that have to be taken into account include establishment of well characterized procedures and platforms along with assessment of analytical variability in addition to the resolution being appropriate for the complexity of the analyzed material [52].
Depending on the complexity of the analyzed system, knockout depths from k = 4 and up to k = 10 are needed.
Last but not least, in order to reduce the complexity of the analyzed parameters in a study enrolling more than 1000 subjects, we did not consider in the investigation the vertical dimensions of the face, which have been also shown to be important in determining the perceived beauty (see Michiels and Sather 1994).
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Mathematical modeling is a powerful tool to address the challenges provided by the complexity of the pathways analyzed in the experiments.
Two types of technical issues influence the interpretation of our results; the first issue concerns the complexity of the tissues analyzed and the second issue concerns the effect of possible incompatibilities between microarray probe sequences and the transcripts under investigation.
Instead, we have attempted to reduce the complexity of the data by analyzing top 10% crosstalk proficient IKK2 or IKK1 profiles separately for peak duration or amplitude.
Linking these two modalities is, however, challenging due to the high complexity of the analyzed biological samples (mainly mammalian tissue sections).
The complexity of the proposed algorithm is analyzed.
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