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Because of the complexity of the analyses, we used only second-degree product terms to assess interaction effects.
To reduce the complexity of the analyses and to identify changes in proteins that could be potentially amenable to monoclonal antibody-based cell sorting or therapeutic-based strategies, we restricted our focus to the cell surface proteome.
Many biologists are used to extraordinary noise in observed datasets and the complexity of the analyses required for testing the LFCH suggest that initial results will be very noisy as well.
We also excluded trials in which fewer than five CHD events and strokes were recorded or the duration of treatment was less than six months, as these data would contribute little to the overall results and substantially increase the complexity of the analyses.
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Due to the complexities of the analyses and results, we provide a summary of the major findings below.
This finding increases the complexity of the genetic analyses of Rb family function in vivo.
Given the complexity of the statistical analyses, large number of possible predictors and the need to account for some missing data in predictor variables, we propose to recruit at least 7000 children in total (two-thirds for algorithm derivation; one-third for validation), in order to maximise the statistical power of the sample).
Agile development of complex workflows in machine learning for drug discovery requires adequate workflow management tools that support the complexity of these analyses.
To reduce the complexity of these analyses, we limited the time resolution of the SEM model to three points in time: baseline, after therapy (12 to 18 months) and at 2 year follow-up (18 to 27 months).
Moving from Tier 1 to Tier 3 increases the accuracy (which is unknown for Tier 1) of the GHG estimates while increasing the complexity of the monitoring and analyses.
This method employed a single hybridization and thus vastly reduced the complexity of the required computational analyses.
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