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This study demonstrates the complexity of formulation design for the engineering of a hybrid lipid-polymer nanoparticle adjuvant.
They are first-order partial-integral differential equations and due to the complexity of formulation, analytical solutions are hard to obtain in the majority of cases.
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However, the complexity of the formulation, the large number of parameters involved, and the difficulty and time required to conduct clay tests make this approach impractical.
Because of the complexity of the formulation for heat integration with varying flows and temperatures, a new targeting approach has been introduced.
Error propagation estimation and analysis of individual models may even be impossible due to the complexity of mathematical formulations, ad hoc assumptions, idealisations of the target system and lack of empirical verification (of parts) of the model.
However, the empirical nature of vaccines and the complexity of many formulations has hindered design of well-defined and easily characterized vaccines.
(13) Given the complexity of RSV formulations and the range of shearing stresses experienced by these semisolids in vivo, characterization should involve a comprehensive rheological evaluation.
Remarkably, the time complexity of formulation (iii) remains O(mn) even for unrooted gene trees (Bansal et al., 2012).
First, the computations of the complex models in both methods are time-consuming because of the complexity of the mathematical formulation.
Here, we compare the complexity of the MDP formulation and the LP relaxation.
Moreover, a multidimensional reduced integration domain (MRID) is proposed to reduce the complexity of the reduced formulation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com