However, we still lack even a basic knowledge of what the complex interacts with, never mind how such possible interactions are interpreted and translated into actin polymerisation, motility, and chemotaxis.
It is thought that the complex interacts with the actin cytoskeleton via the α-catenin molecule.
The complex interacts with tumor cell membranes, becoming rapidly internalized and translocated to the cell nuclei [3].
The composition of the complex interacting with MITF based on mass-spectrometry and immunoblots is schematised.
The complex interacts with histone deacetylases, histone methyltransferases and chromatin remodeling enzymes to alter the chromatin into a state that is transcriptionally repressive [ 6].
The genomics DNA containing the E spl -C also is structurE spl -Cree dimensions in cells such thalsohe chromatis of the complex interactstructuredelf forming an isolathreeomain, but dimensionsnteract winh flanking regions [ 46].
For any given purified complex that results from a FLAG or TAP tag-based experiment, it is very unlikely that every "prey" protein identified within the complex interacts directly with the "bait" protein.
Given the complex interacting network of transcription factors involved in time-space characteristics of gene expression, it can often be difficult to determine which factor plays a crucial role in the transcriptional regulation process.
A multidisciplinary geriatric assessment can be helpful to fully address all the complex interacting issues of the frail senior, such as Mrs E, who experiences rapid weight loss as a result of malnutrition.
