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Application of the COMPARE analysis to the molecular targets database yielded MVP as the second ranked pattern.
Also in the COMPARE analysis to the microarray database MHC class I molecules turned up at high positions in the list.
To test the hypothesis generated by the COMPARE analysis, we used an antitubulin antibody to stain cellular microtubules and examined changes in microtubule dynamics upon compound treatment.
Paullones were initially identified as CDK1/CDK2/CDK5 inhibitors using the COMPARE analysis of a data-base of compounds tested in the National Institute of Health.
This mechanism has also been shown in cardiac toxicity studies for doxorubicin, a DNA topoisomerase inhibitor that correlates to several of the Ir complexes in the COMPARE analysis (see Supplementary Tables 1A F and 2).
The COMPARE analysis was carried out using the NCI/DTP Standard Agents database, a collection of 171 known anticancer compounds, to provide preliminary indications on a possible mechanism of action based on data obtained in a panel of tumor cell lines tested in the 60-cell-line screen in vitro.
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This paper presents the compared analysis of the foaming behaviour and cellular structure of LDPE/hectorite nanocomposites and respective neat LDPE foams.
This is most assuredly not the way to compare analysis techniques.
COMPARE analysis corroborates the similarities between the anticancer agents identified here and various different microtubule inhibitors.
The paper also compares the analysis result of HTR10-GT to those of HTR-10.
The interfacial strength is determined by comparing the analysis results with the experimental results.
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