The autosomal recessive form of RP is the commonest worldwide, accounting for approximately 39% of cases in Spain [ Ayuso et al., 1995].
Both patients carrying functionally significant SMAD6 variants had bicuspid aortic valves, the commonest cardiovascular malformation, occurring in approximately 1% of the adult population.
Australian New Zealand Clinical Trials Registry, ACTRN:12609000420246. Induction of labour (IOL) is one of the commonest obstetric interventions, occurring in approximately 25% of term pregnancies in developed countries [ 1].
Iron deficiency is considered to be the commonest worldwide nutritional deficiency and affects approximately 20% of the world population.
Something about the commonest objects of one generation makes them scarce in the next.
Down syndrome (DS; trisomy 21), the commonest genetic cause of mental disability, affects approximately 250,000 families in the United States alone.
Peritoneal dissemination is the commonest mode of spread, being found in approximately 70% of patients at presentation.
Cystic fibrosis (CF) is the commonest life-threatening genetic disease occurring in approximately 1/3500 white newborns [1].
Lung cancer is one of the commonest neoplasms all over the world with approximately 1.35 million new cases worldwide in 2002 [ 1].
Colorectal cancer (CRC) is one of the commonest malignancies of developed countries [ 1], with approximately 19,000 and 160,000 new cases in the UK and US, respectively, each year, and around 500,000 new cases world-wide [ 2, 3].
