Part of the irregularity in the social class variation in the incidence rates of colon cancer among women may thus be due to differences in use of exogenous hormones.
The discriminability measure should be high when the between class scatter is high and the within class variation is low (samples from the same class are close among them and far from the other classes).
The social class variation among women was smaller than among men, which fits with the pattern of HRT use among wealthier women in the country.
In this study the within class variation for F. verticillioides seemed to be much higher than for the other species as can be seen in the calibration and prediction images in Figs. 5 and 6.
We decided to carry out our study on pooled samples due to the fact that the pool allowed us to eliminate the intra-class variation even if the response of single patients was lost.
They include class variation, denoting the probability that, by means of a distance measure, any two neighbouring data records have a different class value and example cohesiveness, measuring the density of the example distribution in the training set.
We intentionally represented a wide range of age and race in this pilot so as not to over simplify the within-class variation thereby maximizing the specificity of the identified candidate biomarkers.
Interestingly, despite matching age and race between the disease groups, the within-class variation was greater for CIN 3 than for no disease or combined CIN 0 and CIN 1.
This formulation embraces the characteristics mentioned above: class-defining invariance and within class variation, executive stability, and assemblability.
In this paper, we propose a new approach, hierarchical models fusion (HMF), which uses hierarchically multiple simple two-class classification models to represent individually specific parts of the inter-class variation.
