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Lord Patten, BBC Trust chairman, said he believed the agreement would allow further development of "Welsh language broadcast media, to provide a service that truly meets the changes, needs and expectations of the audience".
The clinical relevance of the changes needs to be assessed in a long-term outcome study of renal function.
The patients in the cohort all represent a stable disease state due to their long duration, and the proteins discovered in this study are indeed indicative of their current state, but temporal information about the changes needs to be investigated.
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Other user types may not have the needed access to make the changes need.
The changes needed will not come easily.
Not all the changes need be painful.
"The changes need to account for changes in land-use patterns".
He spoke to the nurse and the respiratory therapist by video and explained the changes needed.
But it is also honest about the challenges involved and the changes needed.
It is now clear that the changes needed will not be implemented before the next election.
The changes needed are often practical, involving tax, planning and the nitty-gritty of regulation.
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