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The more ADCs are being evaluated in preclinical models and clinical trials, the clearer are becoming the parameters and the challenges required for their therapeutic success.
Suitable modifications in the deposition techniques have enabled thin film materials scientists to meet the challenges required for the engineering of the ZnO material with tailored properties by incorporating various dopants and alloying with other oxide materials successfully.
In order to meet the challenges required to protect the values of our waterways, licensing of effluents will need to ensure that there is no disconnect between the core values to be protected and the monitoring system designed to scrutinise performance of the WWTP.
The challenges required them to work together as aligned teams for the first time: "Before the programme, if I needed something I would put in a request and... if no one responded to my request, I would do nothing.... Now our thinking is different.
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"We know that the challenges require some very tough choices in the days ahead.
However, Kerry acknowledged the potential pitfalls, saying last Friday that "the challenges require some very tough choices in the days ahead".
This review of applications sets the stage for a discussion of the challenges requiring further evolution of methodologies.
I find the challenges require energy and patience, which I seem to possess in diminishing supply.
Business can no longer afford to be a bystander, content to sit on the sidelines doing the minimum necessary to acquire its 'licence to operate.' The challenges require -- and citizens demand -- a different approach.
The challenge required him and his fellow celebrities to jump on to a trampoline and glide through the air while grabbing hold of a rope net which hung 60m away.
A recent report used oral challenge of vaccinated mice, but the challenge required a high inoculom in streptomycin and isoflurane-treated mice followed by monitoring CFU in stool for up to 17 days [15].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com