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Moreover, even preclinical research does not offer a clear guidance on development of predictive biomarkers to TRAs; similarly, we are only beginning to appreciate the challenge of predicting sensitivity to IAP inhibitors.
Given the challenge of predicting what leaders like Colonel Qaddafi might do, think of it as a plea for help.
Such is the challenge of predicting a car's allure to tomorrow's collectors.
The challenge of predicting future values of a time series covers a variety of disciplines.
The challenge of predicting traffic flows are the sharp nonlinearities due to transitions between free flow, breakdown, recovery and congestion.
Dr Christopher Dye, the director of strategy in the office of the director general at the World Health Organization, has the challenge of predicting the spread of Ebola.
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The purpose of this paper is to better prepare stakeholders, including future modelers, mine managers, consultants, permitting agencies, land management agencies, regulators, research scientists, academics, and other interested parties, for the challenges of predicting and managing future pit lakes in un-mined areas.
Regulation of genetic tests must take into account the challenges of predicting complex traits.
This highlights the challenges of predicting AF progression and the need for better measures of disease progression.
We also discuss how the framework applies to the inverse model, in order to meet the design challenge of predicting catalyst compositions for desired performance.
Finally, given that the homology (sub models of finger II and III mutants of EGR involved the extra challenge of predicting water-filled cavities at the binding interface, we show how one can use the unprecedented accuracy of our MIP-based code to further validate water positions.
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