I think that's right that the differences between these two cities are directly related to the challenges in understanding how, or under what conditions, cities engage in workshop growth, of the sort that pushes out the production-possibility frontier.
The experiments with the six crudes illustrate the complexity of oil water flows and the challenges in understanding the coupling of surface chemistry and fluid flow.
One of the challenges in understanding CP in human subjects is distinguishing trypsin-dependent and trypsin-independent pathways in CP from the central role of trypsin in acute pancreatitis.
For many diseases the challenges in understanding disease pathogenesis are even greater than for cancer.
One of the challenges in understanding a complex process like carcinogenesis is fitting the different components into a coherent whole.
Though exposure to head trauma is likely the primary predictor of injury, one of the challenges in understanding the effects of repetitive head trauma on brain structure and function is measuring the 'dose' (amount and severity) of exposure.
While there is great expectation and an understandable emphasis on translational research in many quarters, we believe that the challenges in understanding fundamental epigenetics and chromatin processes remain bottlenecks in achieving these goals.
The main challenge in understanding the succession of pathocenoses is finally to determine the spatial scale at which the phenomena must be studied (e.g., at the level of the village or the continent).
Understanding how SpoIIE reads out cellular cues to delay dephosphorylation of SpoIIAA-P until after septation and restrict phosphatase activity to the forespore is thus the central challenge in understanding how cell-specific gene transcription is established during sporulation.
