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Let's look at the central entries.
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Let's look at the central entry, "December 31".
Your hint is at the central entry 66 Across, IT'S RAINING CATS AND DOGS.
I made it all the way to the central entry A TO, including the long down ROSES ARE RED.
WEDNESDAY'S PUZZLE — There's a double trick to today's puzzle, which pays off nicely at the central entry.
It would have been an interesting (note that I said interesting, not nice) touch if all of the clues were FILL IN THE BLANKS, to highlight the central entry.
My favorites were 87 Across's SEALED A KISS (who wouldn't love a chocolatey clue like "Applied foil at the Hershey's factory?"), as well as the slightly creepy I ONLY WANNA BE YOU (clued as "Imposter's excuse?") In nontheme news, I really liked the clue "Chamber exit" for AORTA, and no, I am not going to comment on the central entry in this grid.
When anxiety-related behavior was analyzed, neither young nor adult Syn KO mice significantly differed from control mice in the number of central entries (Fig. 1B).
We take the IFT so as to obtain the vector ṽ = F − 1 Ṽ representing the result of the extrapolation procedure whose M central entries coincide with ( overline{mathbf{v}} ). .
I almost messed up at the central Down entry by filling in A HAIR instead of A NOSE, but then I realized that the person being revealed in the grid would not have hair running down the center of his face unless the reveal was Cousin Itt.
Six scale insect samples were provided from the Central Post-entry Quarantine Station in South Korea.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com