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As the CCPR duration becomes longer, optimal perfusion cannot be maintained until the underlying cardiac defect is corrected.
Of 499 patients suitable for inclusion, 444 and 55 patients were enrolled in the CCPR and ECPR group, respectively.
Of these, 499 patients were included in our study group according to the selection criteria; 444 were included in the CCPR group and 55 in ECPR group.
In this study, a good neurological outcome occurred in 31.7% of patients in the CCPR group with a CPR duration <21 minutes.
Our study showed that the probability of survival to discharge, especially with a good neurological outcome tends to decrease with longer CPR duration in the CCPR group.
Receiver operating characteristic (ROC) curve analysis of CPR duration was used to differentiate between favorable and unfavorable neurological outcomes in the CCPR group.
Similar(43)
However, some exceptions were reported, for example, the CcPR-4 seemed to have a RNase activity mechanism different from those of the type A, B and C RNases [ 35].
The matched ECPR group with ≥ 21 minutes of CPR duration had a more favorable neurological outcome than the matched CCPR group at 3 months post-arrest.
These results suggest that (1) luminal EGF and azoxymethane independently increase the colonic CCPR and their combined effect is not synergistic but antagonistic; (2) EGF may have a role in normal epithelial growth, but does not potentiate colonic carcinogenesis in this model.
The c-statistic of the propensity-score model was 0.999, and the median propensity scores in the ECPR and CCPR groups were 0.39 (SD 0.14) versus 0.10 (SD 0.14), respectively, before matching and 0.39 (SD 0.20) versus 0.34 (SD 0.20), respectively, after matching.
Although ECPR was associated with a better outcome than CCPR, the wide range of outcomes is likely to result from the use of different participant selection criteria, protocols, and strategies, according to relevant regional emergency medical services and hospital response systems [12 15].
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