The PYD of ASC interacts with the PYD of NALP1, and the CARD of ASC recruits the CARD of procaspase-1.
The CARD of Card9 (residues 6-100), tandemndem CARDs of NOD2 (residues 28-215) and the RIP2 CARD (residues 432-534) were amplified by PCR and inserted, using Gateway® cloning, into the expression plasmid pDEST-HisMBP [23].
The C-terminal CARD of ASC facilitates interactions with the CARD of procaspase-1, resulting in its self-activation into caspase 1 by proteolytic cleavage into the active heterodimer comprised of 10 and 10 kDa subunits (p10 and p20, resp).
Homology models of the CARD of murine CARD9 and human CARD9 from residue 6 100 were built using the CARD from CARD11 (PDB 1D: 4I16) [26] as a template.
You take the card of yourself out.
Michael gave me the card of a place called Toy Chin (262 West 77th Street).
"That allows the Israeli side to play the card of preconditions," he said, adding, "The question is how Kerry handles it".
"Just a few of us girls getting together," the hostess said, and handed her the card of announcement, which bore the names of the organizations sponsoring the function.
Conversely, money could be deducted from the card of a child caught scribbling on a bus shelter, or indulging in some other act the government has taken against.
During the last election, he played the card of national identity to fend off a challenge by Ms. Le Pen's father, Jean-Marie Le Pen.
If two players draw cards of the same rank, the card of the higher-ranking suit takes precedence over the other.
