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However, when established spontaneous bursting was examined in the presence of cycloheximide, the duration of the bursting phase was markedly reduced, suggesting that the maintenance of spontaneous bursting in the early hours requires ongoing protein synthesis.
Dissociating perforant path stimuli and intrinsic field discharges in the bursting phase, resulted in no potentiation of the fEPSP, compared to baseline values (Fig. 9A) (ANOVA, p>0.05, n = 6).
ΔSTE tightly correlated with plasticity factor (PF, see methods) values in control animals (Pearsons, r = 0.855; p = 0.0001, n = 28), hence demonstrating that test-pulse-evoked neuronal activity in the bursting phase was the reason for the subsequent LTP (Fig. 6B).
The second period of the bursting phase was formed and characterized by increases, up to the maximal values, of the pre-EPSP current sink and of the positive field potential amplitude (PA), paralleled by a decrement of population spikes (Fig. 6D, E).
The bursting phase is defined by a series of square spikes in which τ1 is the width of the spike and σ1 is the interspike interval.
The period of the signal is given by T = τ2 + σ2, where τ2 is the duration of the bursting phase and σ2 is the quiescent period.
Similar(54)
The quiescent period which separates the bursting phases is given by σ2.
The fact that regular bursting depends on (I_{mathrm{Pump}}) but not (I_{mathrm{CAN}}) and (I_{mathrm{Ca}}) suggests that we can decouple the (I_{mathrm{Pump}} -based burster from the calcI_{mathrm{Pump}} -based regular bursterg phase ofrome SB soluthen.
That is, the increase of (g_{mathrm{Ca}}) will speed up (mathrm{Ca}_{mathrm{i}}) and (mathrm{Ca}_{mathrm{tot}}) (see Table 5) such that the time available for the regular bursting phase becomes shorter and as a result, the number of small bursts decreases.
3.1.2, after first completing some additional analysis of the regular bursting phase with coupling from the calcium compartment to the voltage compartment restored.
We also subdivided the second, bursting phase into two periods (Fig. 6B, C, D).
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