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In light of the breadth of action of LPA, identification of ILMR, an agent that blunts responsiveness to LPA, is likely to guide development of therapeutic strategies to combat cancer and other angiogenesis-dependent pathologies.
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For example, platelet-derived growth factor promotes the proliferation of glioblastoma cells through downregulation of miR-21 [ 12]; the breadth of actions of such an agent is apparent from the observation that it can also enhance glycosaminoglycan elongation on the proteoglycan biglycan and thereby plays a role in the initiation of atherosclerosis [ 13].
The breadth of activity in the Twitter ecosystem is astounding.
Lawmakers should consider the breadth of this action and the degree to which it may create additional obstacles for placing needy children with good parents in a state that already has one of the lowest rates of such placements.
Although the predominant focus of the field has been on outlining the breadth of possible action-game-related enhancements, recent work has concentrated on uncovering the mechanisms that underlie these changes, an important first step towards the goal of designing and using video games for more definite purposes.
Furthermore, the name does not acknowledge the breadth of BMP actions, and it is still not clear what controls and how a specific BMP will be osteoinductive.
Indeed, we have just started to comprehend the breadth of their actions in changing gene expression in normal and abnormal states.
The breadth of Lepidium meyenii's actions on fertility is impressive and range from increased fetal growth, reduced miscarriage rates, improvements in conception rates and increased semen volumes and sperm counts [ 48- 52].
This breadth of action may hinder the usefulness of HDAC inhibitors as therapeutics for genetic disease.
The breadth of improvements reflects the systemic mechanism of action of ivacaftor compared to other therapies.
The breadth of improvements reflects the systemic mechanism of action of ivacaftor compared to other (symptomatic) therapies.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com