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Her sexual encounters with Tuttle, like her efforts to get him to talk like Rey, seem like futile efforts to turn back the clock, to unravel the merciless forward-marching narrative of time: she wants to believe that she can prevent Rey's fateful trip to New York, that she takes his car keys, "hides them, hammers them, beats them, eats them, buries them in the bone soil".
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The bone and soil Hg concentrations are consistent with an interpretation of Hg from the decomposed soft tissue still being present and in-place in the soil now surrounding the skeleton.
When I had last ridden here in late April, jagged cracks ran through the clay and the bone-dry soil turned my bike into a boneshaker.
Realising what we had done, sleeping in Roman coffins, we returned the bones and soil to where we had been sleeping and covered up the ground again.
According to the Stanley Paget "seed and soil" hypothesis, tumor cells as "seed" invading bone provide additional growth factors that activate the bone microenvironment as "soil," which in turn produces growth factors that feed the tumor cells, creating a vicious cycle of destructive mutual cooperation [ 55].
We are all soaked to the bone and the soil has turned to sticky mud.
Metastasis to the bones involves tumor cells (the "seed") invading the bone cavity (the "soil" [8]) and causing a so-called vicious cycle [9].
After metastatic cells have passed through vascular channels and implanted in the bone, a favorable "soil" may be responsible for further growth and proliferation.
To date the sites and study diet and other factors at the site Buckley visited, researchers took smalll samples of bones, soil, plants and other material.
Paget proposed, in 1889, that the affinity of certain cancers to metastasize to bone was due to the fact that the bone provides a 'fertile soil' or environment for the cells to germinate [ 1].
Recently, clinical trials in women with breast cancer suggested that bisphosphonates can improve outcomes by targeting both the seed (the CSCs) and the soil (the bone marrow micro-environment) [ 13- 15].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com