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Baseline results are still confirmed: NENAC and Central Asia are among the lowest participant group in the labor market, while the reservation wage in this subsample is also the lowest for the Central Asian women, and statistically equivalent to the benchmark group for the NENAC women.
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The benchmark groups are those groups of observational studies as abstracted in one of five reviews of VAP incidence [ 1- 5].
Among the benchmark groups, there was no significant trend in VAP-IP versus publication year (data not shown, P = 0.47).
However, for such a risk factor to account for the discrepancies between the VAP-IP of the control groups of SDD studies versus the benchmark groups is unlikely.
The proportion of CNS isolates among the control (p = 0.027) groups of the SDD-RCCT studies is double that versus the benchmark groups.
By contrast, the proportion of Pseudomonas aeruginosa among the bacteremia isolates among the control groups of SDD-RCCT studies is similar to that of the benchmark groups.
However, other reviews applicable to this patient group can be tested against the 95% prediction range derived from the benchmark groups here.
Of the 17 studies identified in these two systematic reviews, only two studies, one from each systematic review, had a control group with a VAP-IP above 47.3%, the upper 95% limit of the prediction range derived from the benchmark groups here, whereas three had an intervention group VAP-IP below the lower 95% limit of the prediction range derived from the benchmark groups.
The disparity between the benchmark groups and the control groups of the SDD studies, which was most apparent for the highest quality studies, could not be explained in the meta-regression models after adjusting for various group level factors.
For the control groups versus the benchmark groups (Table 4; meta-regression models 1 to 3), membership of a control group of an SDD study was a consistently positive predictor.
For the intervention groups versus the benchmark groups (Table 5; meta-regression models 4 to 6), membership of an intervention group of an SDD study was a negative predictor of logit VAP-IP but not consistently significant.
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CEO of Professional Science Editing for Scientists @ prosciediting.com