Sentence examples for the bcr from inspiring English sources

Therefore, the BCR-interacting-kinase Syk is not only required for downstream signaling but also for the opening of the BCR, suggesting that a Syk-BCR inside-out signaling mechanism amplifies the BCR signal in activated B cells [11].

These results were supported by similar effects upon pharmacological inhibition of the BCR pathway using Ibrutinib an inhibitor of the BCR-associated kinase BTK (Supplementary Figure 2a).

This experiment tested whether it is the phosphorylation of the BCR tails by Syk or the binding of Syk to the phosphorylated receptor that opens the BCR oligomer.

Carlos Moyà defeated top-seeded Richard Gasquet of France, 6-2, 6-4, to reach the final of the BCR Open Romania in Bucharest.

If three doses of vaccine were administered the BCR would decrease to 1.3.

The BCR geometry was easily achieved by removing the draft tube of ALR.

Mutations in the BCR-ABL gene are the most common cause of relapse.

The Bcr-Abl oncogenic tyrosine kinase is responsible for initiating and maintaining the leukemia phenotype of CML cells.

They also examined a DNA sequence unique in each case of leukemia, the BCR-ABL1 sequence.

The BCR-ABL protein is known to associate with and activate numerous cellular signaling proteins.

The BCR-ABL tyrosine kinase inhibitor imatinib is highly effective for chronic myeloid leukemia (CML).