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Our results, showing no difference between the baseline function of the NDC and obese groups, obtained with glucose as the only substrate ex vivo, were surprising in view of the serum lipid abnormalities present in vivo in both diet groups after 16 weeks (Table 2), which may have predisposed hearts of obese rats towards fatty acid metabolism.
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For example, functional activity is reduced in reward related brain regions following withdrawal from cocaine self-administration suggesting that there are reductions in the baseline functioning of the system.
Establishing 'reference sites' is a difficult task and a critical factor in determining the baseline functioning of ecosystems.
In this study we sought to establish the baseline functioning of cAMP and the effects of its elevation in DC-derived fibroblasts.
The multivariate analyses for the primary endpoint (Chair Stand Test) and secondary endpoints (pain and function subscales of the KOOS) will control for baseline function of the respective endpoint, age in years, gender, and baseline body mass index.
The most popular class of survival models is the class of proportional hazard models [1,2], where the hazard of an individual at time t is described as the product of the baseline function and of a positive term which is an exponential function of a vector of covariates w′ multiplied by vector of regression parameters θ.
This would serve to essentially flatten the distribution of the baseline function and eliminate the foveal bias.
Graphically, we have shown that the means of the estimates of the baseline hazard function of the three competing events were close to their true baseline hazard functions (Additional file 1, Figures S1 and S2).
41 The baseline cognitive function of the LIFE cohort, measured by the 3MSE, was similar to that of other clinical trials of older adults assessing cognitive outcomes.
The baseline hazard function of the models was stratified by center and age, with age categorized as <25 y, then every 5-y age group, and ≥75 y.
As a consequence, the extent of renal dysfunction following injury is rather dependent on the initial baseline function depicted as the percentage of baseline values normalized to 100% on days 8 and 14 (Table 1).
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