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However, the basal parameters and biological impact of L1-driven mosaicism remain unclear.
Having detailed information regarding the basal parameters and the other mechanistic parameters might further improve the analysis and investigations into the network dynamics.
Dictyostelium cells may be able to expel cytochalasin A through multidrug resistance pumps of the plasma membrane, allowing the cell to restore the basal parameters including a dephosphorylated AdcA.
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The original publication [ 34] contains four different parameter sets and we used parameter set 4 (corresponding to continuous darkness) as the basal parameter set.
In the case of the non-linear dynamic modules, for the basal parameter values (which have already been considered and analyzed before), bifurcation analysis in the parameter S yields robust non-trivial parameter regimes of desired behaviour (eg. bistability, oscillations).
If we assume that all pathways are far from saturation and that basal parameters k r = k y = k x = 0, then in the case where all elements are non-diffusible, we have the steady state response given by (see Appendix B) (17) R ∗ = α S 1 − β α = k xr k sx X tot R tot / k− r k− x ) and β = X tot Y tot R tot k xr k yx k ry / k− r k− x k− y ).
It is frequently thought that significant haemodynamic shifts caused by PCI may affect the ability of basal parameters to detect change after PCI.
After recording of basal parameters, the animals were divided into two groups.
The basal electrical parameters were not altered when concentrations up to 8,000 LD50/mL were incubated in vitro during 60 minutes in the mucosal side of the intestinal tissues (Fig. 2A and 2B).
Table 1 shows the basal clinical parameters and plasma levels of ANP and BNP in the residents with or without the development of CKD.
In order to compare responses from the different null mice and human tissue, we first established the basal electrophysiological parameters of colonic mucosae from mice of each genotype used in this study.
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