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Therefore, the comparison of the applied methodological approaches, the tools used and the examination results between different material objects, is enabled.
Although well carried out, these two studies reported different profiles of miRNA expression, suggesting that both the selection of the samples and the applied methodological approaches could have affected the results.
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We applied methodological restriction to be able to precisely analyse the coincidence of reproductive disorders and burnout: only reproductive disorders (high-risk pregnancies and miscarriages) of the last five years were taken into account.
This report serves as an applied methodological exposition of propensity score weighting that pairs with a forthcoming clinically-oriented report on the associations between a broader set of STIs (including urethral bacterial STIs and syphilis) and HIV [ 14].
The study also applies methodological innovations in the study of disclosure of HIV status by disaggregating disclosure before sex and disclosure after sex [ 29] and by including multiple observations of an individual MSMW's disclosure behaviors.
Moreover, the temporal nature of the effects of scheduled interventions on patient health raises the question of selecting and applying methodological tools appropriate for scientific research in this area.
For several reasons, including ethical quandaries; philosophical differences; lack of infrastructure; and a lack of funding; the humanitarian field has been reticent to apply methodological principles in data collection and application.
Study quality was assessed applying methodological scores: modified Center of Evidence Based Medicine, Newcastle-Ottawa-Scale, and Würzburg Methodological Quality Score.
In particular, we found that included toxicological studies uniformly did not apply methodological approaches that are empirically recognized as minimizing bias in human experimental study outcomes.
In addition, one has to consider that due to methodological limitations, the applied 2D technique might cover only about 20-30% of the total proteome and thus might be complemented in future studies employing LC-coupled mass spectrometric approaches.
The applied approach has initiated a methodological controversy between Auffhammer and Vincent (2012) and Feng and Oppenheimer (2012), with the former contesting this causal relationship based on their own statistical estimations.
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