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The application of microarray platforms applied to miRNA profiling determined their deregulation in virtually all human diseases that have been studied.
Diversity Arrays Technology (DArT) was developed to overcome these and other limitations that prevent the application of microarray technology to non-model organisms.
The application of microarray technology has been stimulating methodological development on data analysis that help biologists to gain more insights into biological functions of genes.
These limitations, which are not unique to ovarian cancer, demonstrate the challenges limiting the application of microarray signatures in cancer care and research, especially in cancers with more limited availability of appropriate tissue resources.
Following the application of microarray technology to genomics, the same technology is now applied to proteomics.
However, the number of samples and cost are the main obstacles to the application of microarray.
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The application of microarrays presents, however, various limitations and challenges for primate neuroscience research.
The chapter focuses on the application of microarrays for the analysis of Mycobacterium tuberculosis inside host cells.
These strategies promise to widen the application of microarrays by permitting the evaluation of hits in a chip-based format.
Of particular interest is the application of microarrays in drug discovery and design to identify 'fingerprints' as potential candidate targets for drug intervention.
The expected improvement in reproductive outcome rates has been reached with the application of microarrays based on comparative genomic hybridization (CGH) in clinical routine PGS.
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