For example, the application of ChIP-on-Chip across a wide diversity of TF's and species is lagging well behind the generation of gene expression data.
The application of ChIP-Seq to histone modification study has proved very useful for understanding the genomic landscape of histone modifications (Barski et al., 2007; Mikkelsen et al., 2007).
Using existing semiconductor technology, this kind of material can allow electrons to move on the surface without energy consumption at room temperature, so the application of this chip to modern transportation will lead to a leap.
It is shown that the application of a chip calorimeter, allowing very fast cooling and heating rates up to 10,000 K/s, can be successfully applied to study reorganization phenomena in crystallizable polymers.
The application of DNA chip technology includes the comprehensive analysis of multiple gene mutations and expressed sequences with regard to newer drug designs, host pathogen interactions and the design of new vaccines.
International collaborations will play an important role in accelerating the pace of discoveries and the application of gene chip technology to urgent problems in ecotoxicology.
The occurrence of S. aurantiaca in soil and mulch was investigated to determine if the application of wood-chip mulch resulted in the introduction of the fungus or the stimulation of an already present population.
The field of toxicogenomics has progressed rapidly since the application of DNA chips to toxicology was proposed in the late 1990s (Afshari et al. 1999).
The explosion in the availability of mutation data, resulting from the application of SNP chips [ 1] and next-generation sequencing [ 2] has led to a huge demand to analyze and predict the effects of mutations.
Thus the application of barcoded ChIP-Seq to globally map transcription factor binding sites in C. elegans and D. melanogaster will be valuable for cost-effective completion of this project.
