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The presence of any mucin outside the appendix excludes the diagnosis of adenoma according to the WHO classification.
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Our quality control steps (detailed in full in the Appendix) sought to exclude suspect samples, poorly genotyped or imputed SNPs, and apparent population outliers.
Benign neoplasms of the colon and rectum (D12), excluding those of the appendix (D12.1), anus and anal canal (D12.9) were identified through HES (England only).
We identified all adults included in the NBCA with a primary diagnosis of bowel cancer, excluding cancer of the appendix, between August 2007 and July 2011 whose record could be linked to HES.
Sensitivity analyses based on the excluded indicators are given in the appendix on bmj.com.
Table A in the appendix provides baseline characteristics of the included and excluded patients.
We hence run our Mincer regression for an alternative sample that excludes individuals below the age of 30 (see Table 21 in the Appendix).
In a robustness check, we excluded all cases that were censored (see Table 16 in the Appendix).
Here we use the prevalence data from the original appendix study, but exclude the data from the NATA study for the model fitting as the most precautionary figure for risk management purposes as advised by the Spongiform Encephalopathy Advisory Committee [19].
The appendix gets a bad press.
Maybe the appendix prompted thoughts of paté.
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