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Haplotype analysis revealed no linkage disequilibrium between the analyzed polymorphisms.
We found that the analyzed polymorphisms are not significantly associated with the disease.
Although the analyzed polymorphisms resulted not associated with migraine, the clinical characteristics of our patients were significantly influenced by the different NOTCH4 genotypes.
All the analyzed polymorphisms were compatible with Hardy-Weinberg expectations.
None of the analyzed polymorphisms was associated with overall risk for postmenopausal breast cancer.
None of the analyzed polymorphisms was associated with risk for breast cancer overall.
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The analyzed polymorphism in this population is the C111T polymorphism in exon 9 (rs769217).
The distributions of allele frequencies for the analyzed polymorphism among studied groups are shown in Table 1.
As observed in the table, the analyzed polymorphism showed no significant association with either the disease or any of the subsets, not even the PAH-positive group.
As shown in Figure 2A, undigested DNA from EPCs or hair root cells yielded two alleles in a MM patient heterozygous for the analyzed polymorphism.
No relevant relationship was observed for the other analyzed polymorphisms.
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