The data collected during the analysis were processed using the BioPharmaLynx software package (Waters).
All data used in the analysis were processed using Accelrys Pipeline Pilot (Accelrys, San Diego, CA, USA) with statistical analysis in the R statistical language (version 2.12.1).
The raw data obtained from the LC MS/MS analysis was processed using Progenesis QI for Proteomics software (version 2.0; Non-Linear Dynamics, a Waters company, Newcastle upon Tyne, UK).
The statistical analysis was processed using SAS System version 6.11 for Windows (SAS Institute, Inc., Cary, NC, USA).
The raw CEL files generated from this analysis were processed using the Qlucore Omics Explorer software package (Qlucore, Lund, Sweden).
The mass spectrometry data analysis was processed using the Proteome Discoverer software (Version 1.3, Thermo Scientific, Bremen, Germany).
A Tabu Search was performed using a tabu list size of 10 and a structural complexity influence of 1. Bayesian analysis was processed using the BayesiaLab 3.3 software (Bayesia SA. Laval Cedex, France).
For clustering analysis, data from the Bluefuse analysis were processed using the Gene Expression Pattern Analysis Suite (GEPAS) [ 146, 147] using the DNMAD and SOTARRAY programs.
Data compilation and analysis were processed using the Diffractometer Management System software package which included a JCPDS powder diffraction database [51].
In this study, factor analysis is processed using the major ion concentrations (Na+, Ca2+, Mg2+, Cl−, SO42− and HCO3−), and the result is shown in Fig. 4.
