From 2528 households approached, 2461 biologically unrelated participants were successfully interviewed; 2385 were included in the analysis (exclusions were aged >65 years).
From 2,528 households approached, 2,461 biologically unrelated participants were successfully interviewed of whom 2,385 met the entry criteria and were included in the analysis (exclusions were aged >65 years).
In relation to maternal age, education, paid occupation, and parity > 1, we found no significant differences among children included in the analysis, exclusions, and those who were lost to follow up (Table 1).
Due to the latter analysis exclusion criteria, the majority of patients defined as having severe CKD will have a renal function just below CrCl 30 mL/min and are not representative of patients with end-stage renal disease.
Of the 42 patients included, 41 were included in the ITT analysis (one consent withdrawal) and 40 were included in the FAS analysis (exclusion of one patient who received HSS infusion within the first six hours; Figure 1).
In the sensitivity analysis, exclusion of lipid lowering drug users slightly enhanced the associations between hypoglycaemia and CVD while it did not change the effect sizes of lipids for CVD although the latter did not reach statistical significance (Table 4).
In the BP analysis, exclusion of individuals with anti-hypertensive medication did not change the regression coefficients.
Nevertheless, there were no differences between groups of individuals included and excluded in the analysis, therefore exclusion of subjects without genotype data probably did not affect the results.
Two participants reached 70 years of age at the time of recruitment were excluded later from the analysis (tertiary exclusion).
We also repeated the analysis after exclusion of all women (cases and controls) who reported 'other' menopause (N=25).
