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The bootstrap- t-test yielded up to 80% lower FDRs than the alternative statistics, and its FDR was always as good as or better than any of the alternatives.
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Calculations are typically done using bioinformatics software such as SNPTEST and PLINK, which also include support for many of these alternative statistics.
We standardized variability statistics across all studies as medians with IQRs, deriving missing medians and IQRs by applying normal distributions on transformations of the reported alternative statistics.
To evaluate the effect of alternative statistics for measuring differential gene expression on enrichment results, we repeated the analysis using the ratio of class means instead of the t-test statistic.
On top of the statistics that DataCite provides, we currently use Google Analytics internally to monitor traffic on the GigaDB Web site, which we hope will enable us to tailor future developments to areas of the Web site that lose traffic, but these data could also provide alternative statistics about the popularity of data sets.
As a result, it may be less powerful and may not be as efficient at detecting departures from neutrality as other alternative statistics hence the reason for implementing Fu and Li's tests.
He was helped by the fact that, instead of conceding the bad news, Cameron just retaliated by firing off alternative statistics of his own, and banging on about the NHS in Labour-run Wales, of course.
Two alternative statistics have been used to estimate the typical level of schooling within an occupation.
Note that some alternative statistics could be used instead of median in step 4. .
Note that some alternative statistics could be used instead of median in step 4. Minor differences in the algorithm setup (size of neighborhood, filter in step 4, number k of uncorrupted pixels in the neighborhood to perform filtering, strategy for handling unprocessed pixels, etc).
Likewise, alternative statistics designed for dominance or recessive penetrance patterns can be used.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com