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lethal with block of the alternative reaction Q00007, EC 1.5.7.1.
The inherent complexity of the alternative reaction schemes in Figure 2 require the use of mathematical models in order to compare their in silico dynamic behavior against the phenotype reported in the literature for different genetically manipulated cell lines.
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With L-serine or glycine, SHMT catalyzes none of the alternative reactions.
The alternative reactions known to be utilized to restore photoheterotrophic growth under these conditions include nitrogenase reaction yielding H2 and sulfate reduction to H2S [ 7, 17].
The first alternative reaction is the conversion of pyruvate to PEP.
The yield of hydrolysis and synthesis has been greatly improved by process design, including immobilization of the enzyme and the use of alternative reaction media.
In fact, human curation of the network is a critical step for the derivation of possible alternative reaction schemes for the ISC biogenesis.
Our results also support the hypothesis of alternative reaction pathways in SABRE that are based on an H/H exchange56,58.
Two papers regard the use of alternative reaction systems.
Lastly, the effect of surface growth is evaluated by comparing the result with an alternative reaction model.
In the first one we consider two simple alternative reaction schemes, namely the Michaelis-Menten and the Henri mechanisms, and aim at invalidating the first scheme with respect to uncertain measurements corresponding to the second one.
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