In order to identify which genetic alterations are functional, the lab of Dr. Dana Pe'er has developed a novel Bayesian probabilistic algorithm, CONEXIC, to integrate copy number and gene expression data in order to identify tumor-specific "driver" aberrations, as well as the cellular processes they affect.
First, sepsis-associated microcirculatory alterations are functional and can be totally reversed.
In the earliest stages, the principal endothelial alteration is merely functional and addressed as "endothelial dysfunction".
Our previous study revealed that the bilateral postcentral gyrus is functional alterations in migraineurs without aura and that the postcentral gyrus has decreased functional connectivity with the contralateral insula, superior parietal lobule, prefrontal cortex and occipital cortex [8].
The alterations are distributed over most of the known functional domains of the respective proteins as seen in the schematic representations presented in the results section.
A common feature of aged organisms is functional alteration and gradual loss of muscle mass and force.
Finally, we have not performed a long-term evaluation or rescanned the subjects yet, so whether the functional alteration is a predictor or a consequence of central sensitization cannot be determined by the present study.
The original public goods game contained the framework for the game, but required a series of alterations before it was functional in the classroom.
Our previous fMRI study demonstrated that some brain regions are functional alterations in migraineurs.
Although the gene alteration was not reported in the NCBI SNP and JSNP databases, pathogenic significance of the gene alteration was also not verified by functional assay.
According to the choice of RS FMRI approach used, the patterns of functional alteration were slightly different.
