The influence of litter must be taken into account in the allocation of test animals as well as the statistical analyses.
When the cost ratio of a targeted test to a routine test increases above a threshold, which is approximately 1.68 for five-year incidence and 1.66 for ten-year incidence, then the optimal allocation of testing resources changes abruptly to all resources allocated to routine testing.
> The optimal allocation of testing resources to minimize five-year incidence for the 5 1 cost ration is shown as a function of δ d and δ v in Fig. 13.
This model is used to find optimal allocations of testing resources, which minimize the total number of new infections over five and ten years.
The optimal allocation of testing resources is a mix of routine testing in high prevalence settings and routine testing in acute care for sufficiently large budget increases or sufficiently high cost ratios.
For example, we showed that optimizing the allocation of all available testing resources after a budget increase could avert 3%to66%66 % more new infections (depending on budget size and relative costs of HIV tests) than optimizing the allocation of new resources only.
The complexity of the tumour genome must also be taken in to consideration, as any abnormal copy number of control probe target sequences will result in the allocation of an inaccurate test probe sequence copy number.
Test B appeared to be less difficult despite the even allocation of test items to both tests.
We increase the total testing budget and optimize the allocation of new resources among the three testing programs, while keeping the allocation of existing resources unchanged.
