Sentence examples for the alleviating interaction from inspiring English sources

For example, the alleviating interaction of CB-132 with CB-194 suggests that the H3K56Ac pathway is involved in relieving DNA damage in the S - phase.

For instance, the maximum scoring function was found beneficial when detecting positive interactions in the GIM dataset (Table 5); however, in more general terms, there seems to be many subtypes of the alleviating interactions, the optimal separation of which may need more tailored screening and classification schemes.

This directional alleviating interaction between the genes reflects the known, consecutive functions of the encoded proteins.

For instance, we detected an alleviating interaction between the APC/C member Cdc23 and the cytokinesis regulator sti.

Note that in the literature this relationship is also referred to as an alleviating interaction, where the phenotype of a double mutant is less severe than expected from the phenotypes of the corresponding single mutants (Jonikas et al., 2009 ; Mani et al., 2008 ).

In addition, we find an alleviating interaction between the H3K56Ac module and S-phase-related module (CB-194), suggesting that the function of H3K56Ac pathway is S-phase-related.

In these cases, I took the mean (this implied that the only two alleviating interactions in the SGI dataset became positive).

Although we focused on the SSL interactions identified in our brc1Δ E-MAP, we did confirm the alleviating (positive) interaction with csi1 (E-MAP = +2.14).

Full data is provided in Additional File 3. We defined phenotypic masking as an alleviating interaction (P < 0.05) where the difference between respective single- and double- deletion mutants for fitness (Δ thr x = |εfit - Wwt/ WY+1| and Δ thr y = |εfit - Wwt/ WX+1|) or sensitivity-based (Δ thr x = |εsen-εenv(Y)| and Δ thr y = |εsen-εenv(X)|) measurements are below a certain threshold (Δ thr).

One example is the interaction between the cell cycle regulators SWI6 and ASH1, which have a strongly alleviating interaction in both environments (εfit = 0.25 and 0.33, respectively), but has a low S-score (εsen = -0.06).

For example, if the double knockdown phenotype of gene A and gene B is similar to the single knockdown of gene A, we call this an alleviating interaction from A to B (A → B).