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A magnet ensures the phone is aligned properly; the mat chirps when the alignment is correct, and again when the phone is removed.
This evidently shows that the classical approach of multiple alignment followed by tree reconstruction is superior only if the alignment is correct.
Some of these tools report a mapping quality score for each alignment in principle, this quality score tells researchers the likelihood that the alignment is correct.
Similar(57)
The first step performs a pre-detection of signatures alignment, and in the second step the alignment is corrected and the signatures are detected by a matcher.
We then manually aligned each positive hit, again using blastx, against the protein to ensure that the alignment was correct.
The sequences were aligned by using the phylogeny tree program [ 15], and the alignment was corrected manually.
The alignment was corrected manually using BioEdit sequence alignment editor (Hall, 1999).
The alignment was corrected manually using BioEdit v7.0.5 [ 103].
The alignment was corrected by hand using SEAVIEW software, and the sequence divergence (dinter) was computed with ClustalW (fig. 1).
The alignment was corrected by hand using SEAVIEW software (Galtier et al. 1996), and the sequence divergence (dintra) was computed with ClustalW (Larkin et al. 2007).
Whenever Sim4 failed to align cynomolgus monkey cDNA sequence with human genome DNA sequence, comparison by BLAST program was executed, and the alignment was corrected manually.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com