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– Find small indels and SNVs in aligned regions (using the alignment information produced by LAGAN).
Extract STRAIGHT spectrum from both source and target speech signals; Apply Mel-cepstral analysis to obtain MFCCs; Perform dynamic time warping on the source and target MFCC sequences to align the speech to obtain the source-target frame pairs; Apply the alignment information to the source and the target spectrums.
The alignment information obtained from traced images can be used to compare the response of neurons to a range of conditions.
After performing recognition with the estimated self-normalization warp, the recognizer feeds back the alignment information so that the self-normalization warp for the next utterance can be estimated (and updated).
Subsequently, the expressed sequences of mRNAs/ESTs overlapping the same RNA editing site were grouped together based on the alignment information.
Each matrix stores the frequency for each nucleotide at every position of the putative motif in order to summarize the alignment information for the TF with a binding site.
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Reads that unambiguously align more closely to the alternate than the original reference are modified to reflect the updated alignment information in the context of the original reference.
The alignment of assembled contigs is then refined using NUCmer and Delta-Filter of the MUMmer 3.0 suite [ 70], and the resulting alignment information is paired with the original contigs and read depth information from YASRA, to be converted into an aligned consensus sequence using sumqual.py and qualtofa.py.
The track alignment information which can be derived from the bogie and car body sensor is investigated by using a mathematical model and the frequency response analysis.
Finally, structural and functional annotations (including known domains from the Interpro database: www.ebi.ac.uk/interpro/) were added using the multiple alignment information management system (MACSIMS) [58].
Bioinformatics approaches to predict the effect of mutations on protein stability utilizes the sequence alignment information of evolutionarily related sequences [51] or protein families or rely on physicochemical modeling of the mutation augmented by information obtained from statistical analyses of protein sequences and three-dimensional structures [52].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com