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The advent of agents who specialize in fashion bloggers points to the evolving influence of blogs.
Page E1 Home FASHION BLOGGERS GO FROM SILLY TO SAVVY The advent of agents who specialize in fashion bloggers points to the evolving influence of blogs.
Barbiturates were frequently used historically as sedatives, induction agents, and for conscious sedation, then became less popular with the advent of agents with shorter duration of action and less lethality in overdose [5, 6].
Treatment of metastatic renal cell carcinoma (mRCC) has improved significantly with the advent of agents targeting the mTOR pathway, such as temsirolimus and everolimus.
One implication of quantifying baseline rates of cardiovascular events in DME is the advent of agents that locally suppress vascular endothelial growth factors (VEGF) in the retina but that may also have systemic effects.
But what is surely open to challenge is whether in an era of much greater understanding of the biology of a disease, and with the advent of agents that are only expected to be active in subsets of patients, the traditional inclusive, phase III design is still the best model to provide a robust estimate of the effect of a novel intervention in the relevant population of patients.
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The advent of targeted agents such as vascular endothelial growth factor tyrosine kinase inhibitors VEGF-TKIs and mammalian target of rapamycin (mTOR) inhibitors led to a change in this paradigm due to improved response rates and progression-free survival, a better safety profile, and the convenience of oral administration.
Prior to the advent of antimicrobial agents, Lemierre's syndrome carried a higher mortality and morbidity.
The advent of antiangiogenic agents has further obfuscated an already difficult problem by producing a new imaging artifact, namely pseudoresponse.
The advent of newer agents, such as paclitaxel, docetaxel, vinorelbine, and gemcitabine have led to the design of potentially more effective preoperative regimens with the ability to advance the cure rate even further.
The advent of these agents represents a significant achievement for the management of hyponatremia.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com