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Although comments were mainly favourable, specific concerns were either that it was a dubious assumption to speculate that it would not be necessary to close the genome or that the advance provided by these results were specific to this particular strain.
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One of the advances provided by the current study is that both col and HA were incorporated into polymeric electrospun scaffolds, and as previously reported, we were able to minimize agglomeration of the HA particles, thus achieving excellent dispersion of nanoscale HA crystals that approximate the size of native bone HA crystals [28].
To be clear, I think the authors have made a very careful and high-quality job, but I am doubtful that the advances provided here represent a major leap rather than a minor incremental change to the state-of-the art.
The canal has offered to stump up a $100m advance provided the contractors contribute the same amount and withdraw their threat to halt work.
Hundreds of fighters from the paramilitary wing of the Kurdistan Worker's Party (PKK) reinforced the peshmerga after the Islamic State advance, providing a much-needed boost in morale and fighting abilities.
Despite the major advances provided by therapy with anti-TNF agents such as infliximab, a significant proportion of patients treated with anti-TNF agents do not respond, and continue to acquire joint erosions and increase in disease activity score 28 (DAS28).
The one-day futures of Ian Bell, Jimmy Anderson and Stuart Broad are being debated, although the Ashes series that starts on 8 July in Cardiff, and the preparation required in advance, provides Whitaker with the perfect softener should they deem them surplus to requirements.
When used judiciously, these advances provide the basis for a viable alternative to the traditional and conservative lower-bound design philosophy of the 1960s.
The centre planned themes and focus areas of the course weeks 6 months in advance, providing us the possibility only to randomise courses each half year and not the total number of courses at once.
The generation of specific monoclonal antibodies and Bcl-G-deficient mice represent a major advance providing the most critical tools for further characterization of the physiological function of Bcl-G.
Many of these advances provide the basis for technologies in use today.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com