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Data on the equivalence between the administration modes was extracted for measures of correlation and mean difference.
The mean EQ-5D-5L utility and VAS scores, and the frequency of respondents endorsing individual EQ-5D-5L dimension response levels did not significantly differ across the administration modes.
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The discrepancy is very likely due to the difference of the administration mode.
The implementation of a distress screening was feasible and highly accepted, regardless of the administration mode.
The computation was not possible for the administration mode and the three character ATC code due to missing cells, caused by the fact that not all administration modes are compatible with all ATC codes.
And the administration mode of delivering a DNA vaccine can influence the type of immune response [ 17] and somehow influence the result of immunoprotective efficacy.
The most common CAEs were disorders of gastrointestinal or general character or were direct associated to the administration mode (Table 3).
In line with a previous study using the OIDP [ 16] and one on EuroQoL [ 35], but in contrast to other relevant studies [ 6, 12- 15], we found no effect of the administration mode on the prevalence estimates of the outcome measure, as shown by the identical Child-OIDP scores between the two administration modes.
Item 1 had DIF between the administration mode subgroups and gender subgroups, where the difference in expected item scores remained relatively large along a large part of the disability continuum.
The administration mode, predicted mortality based on the SAPS3 score, SOFA score at onset of the colistin treatment, clinical and microbiological response, and mortality during the episode of the infection were analysed.
Further basic studies should be focused on optimisation of the dose of ONO-1301SR or the administration mode of ONO-1301SR, such as a single subcutaneous injection, intermittent injections, or oral intake.
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