The representativity of an imaging mass spectrometry experiment, in terms of both chemical representativity and spatial integrity, can only be as good as the worst step in the entire process of sample acquisition, preparation, imaging mass spectrometry, and interpretation.
Instruments of great generality that make few ambiguous assumptions about the nature of extraterrestrial life require luck (e.g., an animal or protist must walk or swim by during the operating lifetime of the camera) or the solution of difficult instrumental problems (e.g., the acquisition and preparation of samples for remote electron microscopic examination).
First, the acquisition and preparation of actual logistics data is performed.
The acquisition and preparation of the datasets are presented in greater detail in Rhrissorrakrai et al. (2014), which also provides further references.
YW, DL, MW, XL, QW, P Zheng, SS, NX, YJ, GZ, RL and P Zhang completed the acquisition or preparation of clinical samples.
The first step involved generating ENMs for each of the two or three inferred chimpanzee populations, which required the acquisition and preparation of chimpanzee presence data from across the study region and the processing of environmental data to define niche dimensions.
Study concept and design: JAK-S, GGC, JH, and DV; acquisition, preparation, analysis, and interpretation of the data: JAK-S and DV; first draft of the manuscript: JAK-S.
MEHL involved in conception and design, obtaining grants, development of questionnaire, acquisition, preparation of dataset, statistical analyses and interpretation of data, drafting the article.
Erythrocyte acquisition, preparation and hemoglobin phenotype determination were described previously [31].
Study design, inadequate sample numbers, and methods of sample acquisition, preparation, storage, processing, and analysis are key areas of possible technical artifacts.
